Organic phosphoric acids and derivatives
Apexbio Technology LLC KN-93 Phosphate 1188890-41-6 1mg
KN-93 Phosphate (CAS 1188890-41-6) is a small-molecule inhibitor targeting calcium/calmodulin-dependent protein kinase II (CaMKII) It is designed to selectively inhibit CaMKII thereby modulating cellular proliferation survival neurotransmitter regulation and related signal transduction pathways KN-93 Phosphate exerts its biological activity primarily by competitively binding to Ca2 /calmodulin disrupting their interaction with CaMKII and preventing CaMKII activation and autophosphorylation In cell-based studies KN-93 Phosphate demonstrates inhibitory activity with IC50 values of 9 M for CaMKII monomer and 3 M for CaMKII dodecamer Experimental models include hepatic stellate cells and NIH 3T3 fibroblasts Based on these pharmacological properties KN-93 Phosphate holds research potential in the study of cell cycle regulation apoptosis neurotransmitter synthesis and neurodegenerative disorders particularly Parkinson s disease models
Medchemexpress LLC Riboflavin phosphate sodium hydrate | 6184-17-4 | 86.4% | 514.36 | 100 G
Riboflavin phosphate sodium hydrate is a derivative of Riboflavin (vitamin B2), an essential nutrient for animals. It is a very effective NAD+-recycling agent and can be used for research on progressive keratoconus, corneal ectasia, and irregular astigmatism.
- Derivative of Riboflavin (vitamin B2)
- Essential nutrient for animals
- Used for research on progressive keratoconus, corneal ectasia, and irregular astigmatism
- Very effective NAD+-recycling agent
Alkali Scientific 4 Nitrophenyl Phosphate bis Cyclohexylammonium Salt, 25 G
Nitrophenyl Phosphate bis Cyclohexylammonium Salt, 25g is a versatile reagent used in biochemical and molecular biology applications. This compound acts as a substrate for various phosphatases and is commonly utilized in enzyme activity assays. The cyclohexylammonium salt enhances the solubility of the compound in different solvents, making it suitable for a broad range of experimental setups. It plays a crucial role in phosphatase assays, protein assays, and enzyme activity studies. The 25g package is ideal for large-scale experiments or for laboratories requiring a bulk supply of the reagent for ongoing applications.
Medchemexpress LLC Riboflavin phosphate sodium hydrate | 6184-17-4 | 86.42% | 514.36 | 5 G
Riboflavine phosphate sodium hydrate is a derivative of Riboflavin (vitamin B2), which is an essential nutrient for animals. It can be used for the research of progressive keratoconus, corneal ectasia, and irregular astigmatism. Riboflavine phosphate sodium hydrate is also a very effective NAD+-recycling agent.
- It is a derivative of Riboflavin (vitamin B2).
- It is an essential nutrient for animals.
- It can be used for the research of progressive keratoconus, corneal ectasia, and irregular astigmatism.
- It is a very effective NAD+-recycling agent.
Alkali Scientific Sodium Phosphate Dibasic, Anhydrous, 500 G
Sodium Phosphate Dibasic, Anhydrous, 500 G is a reagent used primarily in laboratory applications for preparing buffer solutions and adjusting pH levels. The anhydrous form allows for greater accuracy in concentration control, making it ideal for high-precision experiments and applications in fields such as molecular biology, biochemistry, and analytical chemistry. This medium-size 500 G container is perfect for smaller laboratories, specialized research, and educational purposes. Sodium phosphate dibasic plays a key role in ensuring consistent pH conditions during chemical reactions, enzyme assays, and pharmaceutical testing. It is also used in protein purification, HPLC, and other applications requiring stable buffering.
Alkali Scientific Sodium Phosphate Dibasic, Anhydrous, 25 Kg
Sodium Phosphate Dibasic, Anhydrous, 25 Kg is a high-quality reagent used for various laboratory applications. Sodium Phosphate Dibasic is commonly used in buffer solutions to maintain a stable pH environment in chemical and biological experiments. The anhydrous form is preferred when precise concentrations are necessary for applications such as chromatography, molecular biology, and industrial processes. This large 25 Kg quantity makes it suitable for high-throughput laboratories or production settings. Sodium phosphate dibasic serves as an essential buffer component, ensuring proper pH conditions for enzyme reactions, protein purification, and other biochemical applications. It is widely used in the preparation of standard laboratory reagents, cleaning solutions, and in pharmaceutical testing protocols.
Alkali Scientific 4 Nitrophenyl Phosphate Disodium Salt Hexahydrate, 25 G
4-Nitrophenyl Phosphate Disodium Salt Hexahydrate, 25g, is an enzyme substrate widely used in biochemical assays to investigate phosphatase activity. The compound is a reliable substrate for various phosphatases, which hydrolyze phosphoric esters, releasing a p-nitrophenol group detectable via spectrophotometry. This disodium salt form is highly soluble in aqueous solutions, making it ideal for a range of biochemical and molecular biology applications. The 25g quantity is perfect for large-scale laboratory experiments or continuous use, especially in enzyme activity studies, protein assays, and other diagnostic applications in biochemistry and pharmacology.
amino]nonadecanedioate | 5mg | 761506283 | HY-134783 | 905.532 | C57H112N2O5](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502464592.JPG-250.jpg)
eMolecules 2036272-50-9 | Medchem Express | 119-Bis(2-butyloctyl) 10-[[3-(dimethylamino)propyl](1-oxononyl)amino]nonadecanedioate | 5mg | 761506283 | HY-134783 | 905.532 | C57H112N2O5
ChemScene | 2-(3-(Pyridin-4-yl)-1H-124-triazol-5-yl)pyridine | 100mg | 572197035 | CS-0132428 | 36770-50-0 | MFCD00107797 | 223.239 | C12H9N5
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Medchemexpress LLC Fingolimod phosphate | 402615-91-2 | C19H34NO5P | 5 MG
Fingolimod phosphate is an orally active sphingosine 1-phosphate (S1P) receptor agonist. It promotes the neuroprotective effects of microglia and is used for the research of multiple sclerosis and neurologic diseases. In vitro, it prevents lymphocytes from moving out of lymphoid organs and inhibits autoreactive lymphocytes from infiltrating the central nervous system.
- Orally active sphingosine 1-phosphate (S1P) receptor agonist
- Promotes neuroprotective effects of microglia
- Used for research of multiple sclerosis and neurologic diseases
- Prevents lymphocytes from moving out of lymphoid organs
- Inhibits autoreactive lymphocytes from infiltrating the central nervous system
- Downregulates activated microglial production of pro-inflammatory cytokines
- Upregulates microglial production of brain-derived neurotrophic factor and glial cell-derived neurotrophic factor
eMolecules Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(ii) | 14481-08-4 | MFCD00192348 | 5g
Combi-Blocks | Bis(2,2,6,6-tetramethyl-3,5-heptanedionato)nickel(ii) | 5g | 388720044 | QF-1213 | 95.000 | 14481-08-4 | MFCD00192348 | 425.235 | C22H38NiO4
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Apexbio Technology LLC NVP-BGJ398 phosphate 1310746-10-1 100mg
NVP-BGJ398 phosphate (CAS 1310746-10-1) is a potent selective inhibitor of fibroblast growth factor receptors (FGFRs) 1 2 and 3 exhibiting low nanomolar inhibitory activity (IC50 0 9 nM for FGFR1 1 nM for FGFR3 and 1 4 nM for FGFR2) It demonstrates markedly reduced potency against FGFR4 In cellular assays NVP-BGJ398 suppresses autophosphorylation of FGFRs leading to inhibition of downstream signaling pathways such as ERK1/2 The compound effectively reduces proliferation in cancer cell lines harboring FGFR genetic alterations and promotes cell-cycle arrest and apoptosis in cells with FGFR2 mutations NVP-BGJ398 is under investigation in oncology research including phase I clinical trials
Medchemexpress LLC Acetyl phosphate lithium potassium | 94249-01-1 | 98.0% | 10 MG
Acetyl phosphate lithium potassium is an endogenous metabolic product that plays a key role in bacterial metabolic regulation, particularly in lysine acetylation. It is important in bacterial responses to environmental stress and adaptive reactions.
- Plays a key role in bacterial metabolic regulation, particularly in lysine acetylation
- Important in bacterial responses to environmental stress and adaptive reactions
- Regulates lysine acetylation in *Escherichia coli*, promoting protein function, influencing metabolic activities, and affecting cell growth
- Non-enzymatically regulates lysine acetylation of *Salmonella typhimurium* PhoP protein
- Modulates bacterial virulence via acetylation
Medchemexpress LLC trans,trans-Dibenzylideneacetone | 35225-79-7 | 99.9% | 234.30 | 50 G
trans,trans-Dibenzylideneacetone (compound A1) is a dibenzylideneacetone with weak antimalarial activity. It inhibits P. falciparum 3D7 strain with an IC50 of 213.41 μM.
- Exhibits weak antimalarial activity against P. falciparum 3D7 strain with an IC50 of 213.41 μM.
- Shows an IC50 of 13.10 μg/mL against Botrytis cinerea.
- Shows a MIC of 32 μg/mL against B. cinerea.